Selected Publications
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Lubeckyj RA, Sun L. Laser capture microdissection-capillary zone electrophoresis-tandem mass spectrometry (LCM-CZE-MS/MS) for spatially resolved top-down proteomics: a pilot study of zebrafish brain. Mol Omics. 2022 Feb 21;18(2):112-122.
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Xu T, Han L, George Thompson AM, Sun L. An improved capillary isoelectric focusing-mass spectrometry method for high-resolution characterization of monoclonal antibody charge variants. Anal Methods. 2022 Jan 27;14(4):383-393.
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Yang Z, Sun L. Membrane Ultrafiltration-Based Sample Preparation Method and Sheath-Flow CZE-MS/MS for Top-Down Proteomics. Methods Mol Biol. 2022;2500:5-14.
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Yang Z, Zhang Z, Chen D, Xu T, Wang Y, Sun L. Nanoparticle-Aided Nanoreactor for Nanoproteomics. Anal Chem. 2021 Aug 3;93(30):10568-10576.
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Chen D, McCool EN, Yang Z, Shen X, Lubeckyj RA, Xu T, Wang Q, Sun L. Recent advances (2019-2021) of capillary electrophoresis-mass spectrometry for multilevel proteomics. Mass Spectrom Rev. 2021 Jun 15.
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Shen X, Xu T, Hakkila B, Hare M, Wang Q, Wang Q, Beckman JS, Sun L. Capillary Zone Electrophoresis-Electron-Capture Collision-Induced Dissociation on a Quadrupole Time-of-Flight Mass Spectrometer for Top-Down Characterization of Intact Proteins. J Am Soc Mass Spectrom. 2021 Jun 2;32(6):1361-1369.
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Shen X, Liang Z, Xu T, Yang Z, Wang Q, Chen D, Pham L, Du W, Sun L. Investigating native capillary zone electrophoresis-mass spectrometry on a high-end quadrupole-time-of-flight mass spectrometer for the characterization of monoclonal antibodies. Int J Mass Spectrom. 2021 Apr;462.
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Chen D, Yang Z, Shen X, Sun L. Capillary Zone Electrophoresis-Tandem Mass Spectrometry As an Alternative to Liquid Chromatography-Tandem Mass Spectrometry for Top-down Proteomics of Histones. Anal Chem. 2021 Mar 16;93(10):4417-4424.
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Xu T, Shen X, Yang Z, Chen D, Lubeckyj RA, McCool EN, Sun L. Automated Capillary Isoelectric Focusing-Tandem Mass Spectrometry for Qualitative and Quantitative Top-Down Proteomics. Anal Chem. 2020 Dec 15;92(24):15890-15898.
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Yang Z, Shen X, Chen D, Sun L. Toward a Universal Sample Preparation Method for Denaturing Top-Down Proteomics of Complex Proteomes. J Proteome Res. 2020 Aug 7;19(8):3315-3325.
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Chen D, Lubeckyj RA, Yang Z, McCool EN, Shen X, Wang Q, Xu T, Sun L. Predicting Electrophoretic Mobility of Proteoforms for Large-Scale Top-Down Proteomics. Anal Chem. 2020 Mar 3;92(5):3503-3507.
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Yang Z, Shen X, Chen D, Sun L. Improved Nanoflow RPLC-CZE-MS/MS System with High Peak Capacity and Sensitivity for Nanogram Bottom-up Proteomics. J Proteome Res. 2019 Nov 1;18(11):4046-4054.
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Shen X, Yang Z, McCool EN, Lubeckyj RA, Chen D, Sun L. Capillary zone electrophoresis-mass spectrometry for top-down proteomics. Trends Analyt Chem. 2019 Nov;120.
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Lubeckyj RA, Basharat AR, Shen X, Liu X, Sun L. Large-Scale Qualitative and Quantitative Top-Down Proteomics Using Capillary Zone Electrophoresis-Electrospray Ionization-Tandem Mass Spectrometry with Nanograms of Proteome Samples. J Am Soc Mass Spectrom. 2019 Aug;30(8):1435-1445.
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Chen D, Ludwig KR, Krokhin OV, Spicer V, Yang Z, Shen X, Hummon AB, Sun L. Capillary Zone Electrophoresis-Tandem Mass Spectrometry for Large-Scale Phosphoproteomics with the Production of over 11,000 Phosphopeptides from the Colon Carcinoma HCT116 Cell Line. Anal Chem. 2019 Feb 5;91(3):2201-2208.
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McCool EN, Lubeckyj R, Shen X, Kou Q, Liu X, Sun L. Large-scale Top-down Proteomics Using Capillary Zone Electrophoresis Tandem Mass Spectrometry. J Vis Exp. 2018 Oct 24;(140).
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Shen X, Kou Q, Guo R, Yang Z, Chen D, Liu X, Hong H, Sun L. Native Proteomics in Discovery Mode Using Size-Exclusion Chromatography-Capillary Zone Electrophoresis-Tandem Mass Spectrometry. Anal Chem. 2018 Sep 4;90(17):10095-10099.
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Yang Z, Shen X, Chen D, Sun L. Microscale Reversed-Phase Liquid Chromatography/Capillary Zone Electrophoresis-Tandem Mass Spectrometry for Deep and Highly Sensitive Bottom-Up Proteomics: Identification of 7500 Proteins with Five Micrograms of an MCF7 Proteome Digest. Anal Chem. 2018 Sep 4;90(17):10479-10486.
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McCool EN, Lubeckyj RA, Shen X, Chen D, Kou Q, Liu X, Sun L. Deep Top-Down Proteomics Using Capillary Zone Electrophoresis-Tandem Mass Spectrometry: Identification of 5700 Proteoforms from the Escherichia coli Proteome. Anal Chem. 2018 May 1;90(9):5529-5533.
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Lubeckyj RA, McCool EN, Shen X, Kou Q, Liu X, Sun L. Single-Shot Top-Down Proteomics with Capillary Zone Electrophoresis-Electrospray Ionization-Tandem Mass Spectrometry for Identification of Nearly 600 Escherichia coli Proteoforms. Anal Chem. 2017 Nov 21;89(22):12059-12067.
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