2024
March 2024, Congratulations to Jorge for his recent J. Am. Soc. Mass Spectrom. paper. Solid-Phase Microextraction-Aided Capillary Zone Electrophoresis-Mass Spectrometry: Toward Bottom-Up Proteomics of Single Human Cells. He built a reversed-phase-based solid-phase microextraction (RP-SPME)-CZE-MS platform for mass-limited biological samples like single cell proteomics!
January 2024, Congratulations to AmirHossein for his recent Journal of Proteome Research paper. Pilot Evaluation of the Long-Term Reproducibility of Capillary Zone Electrophoresis–Tandem Mass Spectrometry for Top-Down Proteomics of a Complex Proteome Sample. Over 1000 proteoforms were identified per run across 62 runs using one linear polyacrylamide (LPA)-coated separation capillary, highlighting the robustness of the CZE-MS/MS technique!
2023
August 2023, Congratulations to Qianyi for his recent Proteomics paper. Capillary zone electrophoresis-high field asymmetric ion mobility spectrometry-tandem mass spectrometry for top-down characterization of histone proteoforms. Great job!
August 2023, Congratulations to Qianjie for her recent Analytical Chemistry paper. Capillary Zone Electrophoresis-Tandem Mass Spectrometry for Top-Down Proteomics of Mouse Brain Integral Membrane Proteins. The proof-of-concept work demonstrates the high potential of CZE-MS/MS for the large-scale TDP of integral membrane proteins.
June 2023, Congratulations to Tian for her recent Analytical Chemistry paper. And it was invited to be on the supplementary cover! Coupling High-Field Asymmetric Waveform Ion Mobility Spectrometry with Capillary Zone Electrophoresis-Tandem Mass Spectrometry for Top-Down Proteomics.
April 2023, Congratulations to Qianyi for his recent Analytical and Bioanalytical Chemistry paper. Way to go! Pilot investigation of magnetic nanoparticle–based immobilized metal affinity chromatography for efficient enrichment of phosphoproteoforms for mass spectrometry–based top-down proteomics.
Feb 2023, Tian Xu passed her doctoral defense on Advancing Capillary Electrophoresis-Mass Spectrometry for Top-down Proteomics: Technical Development and Biological Applications. Congratulations to Dr. Xu!
Jan 2023, Congratulations to Qianjie for being awarded the 2023 American Society for Mass Spectrometry (ASMS) Graduate Student Travel Awards in ASMS Sanibel Conference!
2022
November 2022, Congratulations to Eli, Tian, and Scott! A new paper about top-down proteomics of cancer cells has been just published online in the journal Science Advances! It is an exciting start for us to study colorectal cancer using top-down proteomics and capillary electrophoresis mass spectrometry. It is fantastic teamwork from the Hummon group at OSU, the Liu group at Tulane University, and the Sun group at MSU.Deep top-down proteomics revealed significant proteoform-level differences between metastatic and nonmetastatic colorectal cancer cells
September 2022, Congratulations to Qianjie for her recent Proteomics paper. This is a collaboration with Dr. Peter Lundquist in BMB department at MSU. Large‐scale top‐down proteomics of the Arabidopsis thaliana leaf and chloroplast proteomes.
July 2022, Congratulations to Tian Xu for being awarded the 2022 American Society for Mass Spectrometry (ASMS) Graduate Student Travel Awards and HPLC 2022 travel grant from the American Chemical Society Subdivision on Chromatography and Separations Chemistry! Well deserved!
June 2022, Congratulations to Tian for her recent Anal Chem paper. Automated Capillary Isoelectric Focusing-Mass Spectrometry with Ultrahigh Resolution for Characterizing Microheterogeneity and Isoelectric Points of Intact Protein Complexes.
February 2022, Congratulations to Rachele for her recent Mol Omics paper. Laser capture microdissection-capillary zone electrophoresis-tandem mass spectrometry (LCM-CZE-MS/MS) for spatially resolved top-down proteomics: a pilot study of zebrafish brain. . 2022 Feb
January 2022, Congratulations to Tian for her recent work, which is featured on the cover of the Anal Methods paper. Improved capillary isoelectric focusing-mass spectrometry method for high-resolution characterization of monoclonal antibody charge variants.
January 2022, Congratulations to Zhichang for his recent Methods Mol Biol paper.Membrane Ultrafiltration-Based Sample Preparation Method and Sheath-Flow CZE-MS/MS for Top-Down Proteomics.
2021
August 2021, Consortium for Top-Down Proteomics launched a new initiative for the CE-MS of intact proteins and protein complexes. The Initiative is being led by Liangliang Sun of Michigan State University, Alexander R. Ivanov of Northeastern University, and Kevin Jooss of Northwestern University.
August 2021, Congratulations to Zhichang for his recent paper on Anal Chem. Nanoparticle-Aided Nanoreactor for Nanoproteomics.
July 2021, Prof. Liangliang Sun has received the Thermo Fisher Scientific Early Career Award from the 37th International Symposium on Microscale Separations and Bioanalysis (MSB 2021). The award is “…the inaugural award given to an individual for remarkable research achievements, with particular consideration being given to the development of new methods, techniques, and high-impact applications in the field of microscale separations and bioanalysis.”
May 2021, Zhichang Yang passed his doctoral defense on DEVELOPING ULTRASENSITVE MS-BASED PROTEOMIC PLATFORMS FOR THE CHARACTERIZATION OF MASS-LIMITED SAMPLES. Congratulations to Dr. Yang!
June 2021, Check our recent review on Mass Spectrom Rev! Recent advances (2019-2021) of capillary electrophoresis-mass spectrometry for multilevel proteomics.
June 2021, Congratulations to Xiaojing and Tian for their J Am Soc Mass Spectrom paper. This is a collaboration with Prof. Joseph Beckman at e-MSion and Oregon State University. Capillary Zone Electrophoresis-Electron-Capture Collision-Induced Dissociation on a Quadrupole Time-of-Flight Mass Spectrometer for Top-Down Characterization of Intact Proteins.
April 2021, Congratulations to Tian for her recent Front Chem paper. A Mini Review on Capillary Isoelectric Focusing-Mass Spectrometry for Top-Down Proteomics. .
April 2021, Congratulations to Xiaojing for her recent Int J Mass Spectrom paper. This is a collaboration with Prof. Wenjun Du group at Central Michigan University. Investigating native capillary zone electrophoresis-mass spectrometry on a high-end quadrupole-time-of-flight mass spectrometer for the characterization of monoclonal antibodies.
March 2021, Congratulations to Zhichang for his recent Anal Methods paper. Recent technical progress in sample preparation and liquid-phase separation-mass spectrometry for proteomic analysis of mass-limited samples.
March 2021, Daoyang Chen passed his doctoral defense on Method development for capillary electrophoresis mass spectrometry (CE-MS)-based proteomics and application to uncovering proteome dynamics of zebrafish embryos during early embryogenesis. Congratulations to Dr. Chen!
March 2021, Congratulations to Daoyang for his recent Analytical Chemistry paper. Capillary Zone Electrophoresis-Tandem Mass Spectrometry As an Alternative to Liquid Chromatography-Tandem Mass Spectrometry for Top-down Proteomics of Histones. A
February 2021, Rachele Lubeckyj passed her doctoral defense on Highly Sensitive Qualitative And Quantitative Top-Down Proteomics Using Capillary Zone Electrophoresis - Electrospray Ionization-Tandem Mass Spectrometry. Congratulations to Dr. Lubeckyj!
January 2021, Dr. Liangliang Sun has been recognized as one of the Rising Stars in Proteomics and Metabolomics by the ACS Journal of Proteome Research, one of the leading publications in proteomics.
2020
December 2020, Congratulations to Tian for her recent Analytical Chemistry paper. Automated Capillary Isoelectric Focusing-Tandem Mass Spectrometry for Qualitative and Quantitative Top-Down Proteomics.
December 2020, Xiaojing Shen passed her doctoral defense on Leveraging capillary zone electrophoresis-mass spectrometry for multi-level proteomics. Congratulations to Dr. Shen!
August 2020, Congratulations to Zhichang for his recent Journal of Proteome Research paper. Toward a Universal Sample Preparation Method for Denaturing Top-Down Proteomics of Complex Proteomes.
Congratulations to Xiaojing Shen for being awarded the 2020 American Society for Mass Spectrometry (ASMS) Graduate Student Travel Awards and the spring semester 2020 College of Natural Science Dissertation Continuation Fellowship! Well deserved!
March 2020, Congratulations to Zhichang for his recent Journal of Proteome Research paper (https://pubs.acs.org/doi/10.1021/acs.jproteome.9b00840). This is a collaboration with Prof. Lubman group at UM.
February 2020, Congratulations to Daoyang for his recent Analytical Chemistry paper on the prediction of proteoform electrophoretic mobility (https://pubs.acs.org/doi/10.1021/acs.analchem.9b05578)
Congratulations to Elijah McCool for being awarded the 2019 American Society for Mass Spectrometry (ASMS) Graduate Student Travel Awards!